Research

Below is a selection of works across several research themes. A comprehensive list of publications can be found on my Google Scholar page.

AI in Surgery

Varghese C, Harrison EM, O’Grady G, Topol EJ. Artificial Intelligence in Surgery. Nature Medicine.

Varghese C, Habermann EB, Hanson K, Choudhary A, Salehinejad H, Thiels CA. Tabular foundation models as a new portable standard in local surgical risk prediction. Surgery.

Varghese C, Choudhary A, Starlinger P, Kendrick M, Smoot R, Warner SG, Truty M, Habermann EB, Salehinejad H, Thiels CA. Dynamic prediction of early discharge after major pancreatic surgery. Surgery.

Varghese C, Peters L, Gaborit L et al., on behalf of the TASMAN Collaborative. Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model. npj Digital Medicine.

Surgical Recovery

McLean KA, Knight SR, Diehl TM, Varghese C, Ng N, Potter MA, Zafar SN, Bouamrane MM, Harrison EM. Readiness for implementation of novel digital health interventions for postoperative monitoring. Lancet Digital Health.

Dawes AJ, Lin AY, Varghese C, Russel MM, Lin AY. Mobile health technology for remote home monitoring after surgery: a meta-analysis. BJS.

Wells CI, Varghese C, Boyle L, McGuinness MJ, Keane C, O’Grady G, Gurney J, Koea J, Harmston C, Bissett IP. Failure to Rescue” following colorectal cancer resection. Annals of Surgery.

Varghese C, Wells C, O’Grady G, Christensen P, Bissett I, Keane C, on behalf of the Longitudinal LARS Group. The Longitudinal Course of Low-anterior Resection Syndrome: An individual Patient Meta-analysis. Annals of Surgery.

Varghese C, Bhat S, Wang TH, O’Grady G, Pandanaboyana S. Impact of gastric resection and enteric anastomotic configuration on delayed gastric emptying after pancreaticoduodenectomy: a network meta-analysis of randomized trials. BJS Open.

Translational GI Physiology

Varghese C, Schamberg G, Calder S, Waite S, Carson D, Foong D, Wang W, Ho V, Woodhead J, Daker C, Xu W, Du P, Abell T, Parkman HP, Tack J, Andrews CA, O’Grady G, Gharibans AA. Normative values for body surface gastric mapping evaluations of gastric motility using Gastric Alimetry. American Journal of Gastroenterology.

Varghese C, Pasricha PJ, Abell T, Parkman HP, Andrews CN, Kesthelyi D, Gharibans AA, Farrugia G, O’Grady G. Spectrum of interstitial cell of Cajal deficits in chronic gastroduodenal disorders. American Journal of Gastroenterology.

Gharibans AA, Calder S, Varghese C, Waite S, Schamberg G, Daker C, Du P, Alighaleh S, Carson D, Woodhead J, Farrugia G, Windsor JA, Andrews CN, O’Grady G. Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device. Science Translational Medicine.

Student and Trainee-Led Collaboratives

TASMAN Collaborative. Patterns of opioid use after surgical discharge: a multicentre, prospective cohort study in 25 countries. Anaesthesia.

STRATA Collaborative. Variation in the practice of cholecystectomy for benign biliary disease in Aotearoa New Zealand. HPB.

EuroSurg and STARSurg Collaborative. Global Use and Outcomes of Endoscopic Stenting in Acute Malignant Left-Sided Colonic Obstruction: A Secondary Analysis of APOLLO, An International, Prospective Cohort Study. Diseases of the Colon and Rectum.